The Microbiology Of Lyme Disease - 2421 Words

What is the first thing you think of when you hear Lyme disease? I asked my brother, just for fun, to see what his response would be, and his response was too good not to share. He said â€Å"Yeah, Lyme disease is when limes turn gross.† I can’t make this up! Sorry, Landon, not quite. Lyme disease is a rather increasing epidemic, not only in Iowa but also in great numbers on the east coast states. Throughout this paper, I will be discussing what Lyme disease is, the microbiology of Lyme disease, how one can get it, the typical signs and symptoms, typical treatments, and some epidemiology of this bacterial infection. Like we established earlier, Lyme disease is not what makes limes gross but in fact, Lyme disease is a bacterial infection†¦show more content†¦It has a spiral, helix shape with a double membrane resembling gram-negative bacteria when stained. When gram stained, it resembles gram-negative bacteria because it holds the safrin in its outer membr ane but the composition is much different than that of a gram negative cell. A gram negatives cell wall is made of lipopolysaccharides, whereas the outer membrane of a spirochete is made of scattered lipoproteins throughout. B. burgdorferi is also unable to live without a host, it is classified as a chemoheterotroph, relying on other sources for their amino acids, fatty acids, and other nutrients. Like I mentioned earlier, spirochetes have 2 membranes, with periplasmic space between each. Here, the bacteria carry their mode of transportation. They have endoflagella which are almost ‘hidden’ within the periplasmic space. They move in a cork-screw like fashion and are able to go almost undetected by the host immune response because of such. Also, because of the mode of motility, spirochetes are able to burrow deep into very viscous tissues like muscles and even cartilage. This makes spirochete hard to target, and hard to find as well. Normal antibodies cannot eve n get through cartilage, leaving the spirochete to carry out their destruction of the cells. Normally, flagella are antigenic, meaning they are something detected as foreign to the body and it elicits an immune response. Because theShow MoreRelatedDescriptive and Analytic Epidemiology1317 Words   |  6 PagesDescriptive and Analytic Epidemiology TUI University Lea Glover MPH 504 Descriptive and Analytic Epidemiology Case Assignment #3 Dr. Sharon Nazarchuk Abstract Descriptive epidemiology is defined as the study of the amount and distribution of disease within a population by person, place, and time. Descriptive epidemiology answers the following questions: Who is affected? Where and when do cases occur? It describes cases by person, place, and time (TUI University 2008). 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